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Su poblacin bacteriana tambin cambi completamente, si bien al volver a la Tierra regres a su estado inicial. El cuerpo de Scott Kelly sufri otros cambios, como mayor presin intracraneal y problemas visuales, as como mutaciones genticas, una considerable reduccin de la masa corporal en comparacin con la de su hermano y cambios cognitivos relevantes. Aunque an no hay resultados definitivos, este experimento ha permitido ver como nunca los efectos en el cuerpo humano de las difciles condiciones en el espacio.

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