The early varieties were made of thin tubes of glass with mercury, and were mounted to ivory or wood.3 of 19Photos: The health game changers of the last 500 yearsFace transplants Plastic surgeons date the first nose job as far back as the 1400s, but developments in this area of surgery would have to wait until the practice of the skin graft was honed in the late 1800s. Even then, it would take another two centuries before doctors were able to apply this technology to transplanting parts of the face. French doctors did a partial facial transplant in 2005, and three years later, doctors at the Cleveland Clinic performed the world’s first full facial transplant..
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